Autobytel.com runs dozens of webservers in a farm with millions of hits per day. They have had no problems and are actually converting their stuff to Fusebox.
ToysRus.com (now all part of amazon.com's backbone), which at one point was running over 100 webservers handling their traffic at xmas shopping season was another example. You cynics out there might say that toysrus.com went down a lot that season. I've heard from the lead programmer there (a one Mr. Medinets) that the reason they went down is because an Allaire Consultant came out to their site, checked out the application and recommended a certain number of CF servers to handle their expected load. Well along came the expected load and those servers died - too many hits. After getting a bunch of servers overnighted from Dell, toysrus.com was successful.
Finally, my own little piece of scalable news: I recently built a prom dress retail site (last fall) in Fusebox and CF. When I finished it, we were already getting 10,000 hits per day. A few months later (after ads appeared in seventeen magazine) I reviewed the WebTrends reports and we were averaging 500,000 hits per day on one dual-proc server. Peak days were 1 million plus hits. Site was always really fast. I recieved no errors for months from that site.
Therefore, CF and Fusebox are both enterprise worthy.
Check out http://fusebox.org/Files/presentations/Scalability.ppt for Doug Nottage's (lead tech dude at autobytel) presentation on scalability. It's very thorough.
NAT
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Nat Papovich